【Detection Purpose】
D-dimer is the simplest fibrin degradation product, and elevated D-dimer levels indicate
hypercoagulability and secondary hyperfibrinolysis in vivo. Therefore, D-dimer
concentration is of great significance for the diagnosis, efficacy evaluation and prognosis
of thrombotic diseases.
【Detection principle】
This product uses fluorescence immunochromatography to quantitatively detect the Ddimer
content in serum/plasma. Basic principle: The nitrocellulose membrane is marked
with T and C lines, and the T line is coated with antibody A that specifically recognizes
D-dimer. The binding pad is sprayed with another fluorescent nanomaterial-labeled
antibody B that can specifically recognize D-dimer, and the D-dimer in the sample first
binds to the nanomaterial-labeled antibody B to form a complex, and then upward
chromatography, the complex binds to the T-line antibody A to form a sandwich
structure, and when the excitation light is irradiated, the nanomaterial emits a fluorescent
signal, and the strength of the signal is positively correlated with the concentration of Ddimer
in the sample.