【Detection purpose】
IgE is a type of immunoglobulin (Ig) with a molecular weight of 188kD and a very low
content in serum. It is usually used for the diagnosis of allergic reactions. In addition, it
can also assist in the diagnosis of parasitic infections and multiple myeloma. 1. Allergic
reaction: When an allergic reaction occurs, the allergen IgE rises. The higher the allergen
IgE, the more serious the allergic reaction. 2. Parasite infection: After a pet is infected by
a parasite, the allergen IgE may also increase, which is generally related to the mild
allergy caused by the parasite protein. In addition, the presence of a tumor in the report
may also lead to elevated total IgE.
【Detection principle】
This product uses fluorescence immunochromatography to quantitatively detect the
cTIgE content in serum/plasma. Basic principle: T and C lines are drawn on the
nitrocellulose membrane respectively, and the T line is coated with antibody a that
specifically recognizes cTIgE antigen. Another fluorescent nanomaterial-labeled
antibody b that can specifically recognize cTIgE is sprayed on the binding pad. The
cTIgE in the sample first combines with the nanomaterial-labeled antibody b to form a
complex, and then the upward chromatography, the complex and T-line antibody a
Combined to form a sandwich structure, when the excitation light is irradiated, the
nanomaterial emits a fluorescent signal, and the strength of the signal is positively
correlated with the concentration of cTIgE in the sample.
.【Main ingredients】
1. cTIgE Detection Reagent Card
2. Sample diluent
3. Tip
4. Instructions, etc